In process development, the ability to scale efficiently without compromising performance is critical. The 5 L Thermo Scientific™ DynaDrive™ Single-Use Bioreactor (S.U.B.) introduces a new standard by offering high-performance scalability starting at just 1 L, setting it apart from traditional glass bioreactors.
Scalable from 1 L: A Game-Changer for Process Development
With a 5:1 turndown ratio and a minimum working volume of 1 L, the 5 L DynaDrive S.U.B. enables flexible experimentation without vessel changes. Its design and film match those of the larger 500 L and 5,000 L DynaDrive S.U.B.s, delivering consistent mass transfer and mixing across scales. This uniformity simplifies process transfer, supports global standardization, and accelerates time to production.
A Cost-Effective, Eco-Friendly Solution
By removing the need for cleaning and sterilization and supporting faster development cycles, the 5 L DynaDrive S.U.B. offers both economic and environmental benefits. It reduces labour, water, and energy usage while increasing throughput—aligning with the growing demand for sustainable bioprocessing solutions. Unlike glass bioreactors, the pre-sterilized BioProcess Container (BPC) eliminates cleaning and sterilization, reducing contamination risk and cutting workflow time by up to 20%. The result? Up to 27% more productivity and a lower environmental footprint.
Designed for High-Performance Cultures
Equipped with a proprietary drilled-hole sparger and advanced drivetrain, the system ensures efficient mass transfer, ideal for fed-batch and perfusion applications. Paired with Gibco™ media and supplements, it consistently supports high-density cell cultures with improved viability and yield.
Easy to Use, Built to Scale
With its front-loading BPC, aseptic connectors, and compact cubic design, the 5 L DynaDrive S.U.B. is operator-friendly and space-efficient. Its similarity to larger DynaDrive units ensures easy scale-up, with larger models offering 10:1+ turndown ratios for smooth transition to commercial production.
Conclusion: One Platform, From Lab to Launch
The 5 L DynaDrive S.U.B. delivers scalable, efficient, and consistent performance starting at 1 L—empowering teams to move faster and smarter from process development to production. It’s a future-ready solution for biologics, cell therapies, and more.
The new 5L Dyna Drive is part of the existing range, just a new size.
